Shintaro Iwama Selected Research

Leptin

1/2022	Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin.
12/2021	Peripheral combination treatment of leptin and an SGLT2 inhibitor improved glucose metabolism in insulin-dependent diabetes mellitus mice.
1/2021	High-fat Feeding Causes Inflammation and Insulin Resistance in the Ventral Tegmental Area in Mice.

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Shintaro Iwama Research Topics

Disease

14	Neoplasms (Cancer) 12/2023 - 02/2013
9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2024 - 01/2021
7	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 01/2024 - 06/2017
5	Inflammation (Inflammations) 09/2022 - 04/2014
5	Thyroiditis 01/2022 - 09/2012
5	Hypothyroidism 01/2022 - 08/2012
5	Hyponatremia 01/2017 - 12/2010
4	Type 2 Diabetes Mellitus (MODY) 12/2023 - 01/2020
4	Diabetes Insipidus 03/2023 - 06/2017
4	Polyuria 03/2023 - 06/2017
4	Hypophysitis 11/2020 - 04/2014
3	Thyrotoxicosis 04/2024 - 11/2018
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2021 - 01/2017
3	Obesity 01/2021 - 10/2019
3	Melanoma (Melanoma, Malignant) 01/2020 - 04/2014
2	Headache (Headaches) 05/2024 - 01/2017
2	Adrenal Insufficiency (Adrenal Gland Hypofunction) 03/2023 - 01/2017
2	Hypopituitarism (Sheehan's Syndrome) 01/2023 - 01/2021
2	Hyperglycemia 01/2022 - 01/2020
2	Latent Autoimmune Diabetes in Adults 01/2022 - 10/2021
2	Insulin Resistance 01/2021 - 01/2017
2	Bulimia (Binge Eating) 01/2021 - 10/2019
2	Autoimmune Hypophysitis 06/2017 - 07/2015
2	Hashimoto Disease (Thyroiditis, Hashimoto) 01/2015 - 09/2012
2	Demyelinating Diseases (Demyelinating Disease) 11/2014 - 12/2010
1	COVID-19 05/2024
1	Vomiting 05/2024
1	Malignant Mesothelioma 02/2024
1	Interstitial Lung Diseases (Interstitial Lung Disease) 02/2024
1	Skin Manifestations 02/2024
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024
1	Carcinoma (Carcinomatosis) 12/2023
1	Hyperthyroidism 01/2022
1	Graves Disease (Basedow Disease) 01/2022
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 05/2021
1	Infections 05/2021
1	Addison Disease (Addison's Disease) 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Glucose Intolerance 01/2021
1	Hypoparathyroidism 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 11/2020
1	Dehydration (Water Stress) 11/2020

Drug/Important Bio-Agent (IBA)

10	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2017
10	AntibodiesIBA 01/2022 - 04/2014
7	Insulin (Novolin)FDA Link 12/2023 - 01/2020
6	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 01/2020
6	Arginine Vasopressin (Argipressin)IBA 03/2023 - 01/2018
5	Vasopressins (Vasopressin)IBA 01/2024 - 11/2014
4	NivolumabIBA 02/2024 - 03/2018
4	Messenger RNA (mRNA)IBA 09/2022 - 03/2011
3	Streptozocin (Streptozotocin)FDA Link 12/2023 - 12/2021
3	LeptinIBA 01/2022 - 01/2021
3	Thyroglobulin FDA Link 12/2021 - 09/2012
2	Thyroxine (Levothyroxine)FDA LinkGeneric 04/2024 - 03/2018
2	Mutant Proteins (Protein, Mutant)IBA 01/2024 - 01/2018
2	EpitopesIBA 01/2023 - 01/2015
2	B7-H1 AntigenIBA 01/2022 - 05/2021
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2020
2	LigandsIBA 01/2022 - 01/2017
2	CTLA-4 AntigenIBA 01/2022 - 04/2014
2	AutoantibodiesIBA 10/2021 - 10/2013
2	gamma-Aminobutyric Acid (GABA)IBA 01/2021 - 10/2019
2	AutoantigensIBA 11/2020 - 03/2018
2	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2020 - 04/2014
2	Interleukin-10 (Interleukin 10)IBA 01/2020 - 02/2017
2	CytokinesIBA 01/2020 - 03/2011
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 11/2018 - 04/2014
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2011
2	IpilimumabIBA 01/2015 - 04/2014
2	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 11/2014 - 12/2010
2	Minocycline (Cyclops)FDA LinkGeneric 11/2014 - 12/2010
1	COVID-19 VaccinesIBA 05/2024
1	ChemokinesIBA 12/2023
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 12/2023
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2023
1	Aquaporin 2IBA 03/2023
1	AldosteroneIBA 03/2023
1	MineralocorticoidsIBA 03/2023
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2023
1	Amino Acids FDA Link 01/2023
1	Histocompatibility Antigens Class IIIBA 01/2023
1	ProinsulinIBA 01/2023
1	RamucirumabIBA 01/2022
1	Tyrosine Kinase InhibitorsIBA 01/2022
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 01/2022
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	Thyroid HormonesIBA 01/2022
1	Sodium-Glucose Transport ProteinsIBA 12/2021
1	Sodium-Glucose Transporter 2 InhibitorsIBA 12/2021
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 10/2021
1	atezolizumabIBA 05/2021
1	Dietary Sodium Chloride (Table Salt)IBA 01/2021
1	Leptin ReceptorsIBA 01/2021

Therapy/Procedure

4	Aftercare (After-Treatment) 01/2022 - 01/2015
3	Glycemic Control 12/2023 - 01/2020
3	Immunotherapy 01/2017 - 04/2014
1	Transplantation 01/2023
1	Therapeutics 01/2022